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Innate immune functions in kidney transplantation Berger, S.P.

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Citation

Berger, S. P. (2009, January 28). Innate immune functions in kidney transplantation. Retrieved from https://hdl.handle.net/1887/13439

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden

Downloaded from: https://hdl.handle.net/1887/13439

Note: To cite this publication please use the final published version (if applicable).

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Innate Immune Functions in Kidney Transplantation

Stefan Philip Berger

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Copyright © 2009 S.P. Berger

All rights reserved. No part of this thesis may be reproduced or transmitted in any form, by any means, electronic or mechanical, without the prior written permission of the author, or where appropriate, of the publisher of the articles.

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Innate Immune Functions in Kidney Transplantation

Proefschrift

ter verkrijging van

de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magni cus prof.mr. P.F. van der Heijden,

volgens besluit van het College voor Promoties te verdedigen op woensdag 28 januari 2009

klokke 16.15 uur

door

Stefan Philip Berger

geboren te Johannesburg in 1969

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Referent: Prof.Dr. I. J. ten Berge

Academisch Medisch Centrum, Universiteit van Amsterdam

Overige leden: Prof.Dr J.A. Bruijn, Prof.Dr. F.H.J. Claas

Dr. L.B. Hilbrands, Universitair Medisch Centrum St Radboud, Nijmegen

Prof.Dr. T.W.J. Huizinga, Dr. C. van Kooten

Prof.Dr. G.J. Navis, Universitair Medisch Centrum Groningen

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Voor Tanja

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Contents

Chapter 1 Introduction and scope of the thesis 9

Chapter 2 Complement and the Kidney 15

Nephrology Dialysis Transplantation 2005; 20:2613-2619

Chapter 3 Association between Mannose-binding Lectin Levels and 31 Graft Survival in Kidney Transplantation

American Journal of Transplantation 2005; 5:1361-1366

Chapter 4 Low Pre-transplantation Mannose-binding Lectin Levels Predict 47 Superior Patient and Graft Survival after Simultaneous

Pancreas-kidney Transplantation

Journal of the American Society of Nephrology 2007; 18:2416-2422

Chapter 5 Infectious complications after simultaneous pancreas-kidney 65 transplantation: A role for the lectin pathway of

complement activation Transplantation 2008; 85:75-80

Chapter 6 Properdin binds to late apoptotic and necrotic cells 83 independently of C3b, and regulates alternative pathway

complement activation

Journal of Immunology 2008; 180(11):7613-7621

Chapter 7 Complement activation by tubular cells is mediated by 111

properdin binding

Am J Physiol Renal Physiol 2008; 295(5):F1397-403

Chapter 8 General Discussion 131

Nederlandse samenvatting 145

Curriculum vitae 149

Publications 150

Nawoord 152

Color gures 153

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