(1)Cover Page The handle http://hdl.handle.net holds various files of this Leiden University dissertation

Title: Functional xylem anatomy: intra and interspecific variation in stems of herbaceous and woody species. Issue

Title: Early intervention in children at high risk of future criminal behaviour: Indications from neurocognitive and neuroaffective mechanisms. Issue

Title: Volatile compounds from Actinobacteria as mediators of microbial interactions Issue

In chapter 4, an attempt is made to reproduce the observed clinical response following administration of the monoclonal antibody trastuzumab in an ex vivo stimulation test,

The publication of this thesis was financially supported by the foundation Centre for Human Drug Research (chdr) in Leiden, the

of biopharmaceuticals Published (in modified form) in the European journal of drug metabolism and pharmacokinetics, 2018, volume 43, issue 1..

First, a combined model was developed and similarity between test and reference product was evaluated by performing a covariate analysis with trastuzumab drug product (test

transport by the flow of the medium, in this case laminar flow.23 There may be a blunting effect on the net delivery caused by dif- fusion of the drug from the infusate