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Structural biology of induced conformational changes

Geus, D.C. de

Citation

Geus, D. C. de. (2009, June 4). Structural biology of induced conformational changes.

Retrieved from https://hdl.handle.net/1887/13826

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden

Downloaded from: https://hdl.handle.net/1887/13826

Note: To cite this publication please use the final published version (if applicable).

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133 Curriculum vitae

Daniël de Geus was born in Utrecht, the Netherlands on the 26th of June 1977. Immediately after his secondary education at College Blaucapel in Utrecht (1989-1995) he joined the Wageningen University. During his study Molecular Sciences he chose the combined microbiological/biochemical specialization. The master thesis ‘Purification and characterization of chlorate respiration key enzymes from bacterial strain GR-1’ was written about a research project conducted at the Bioinorganic Chemistry group, supervised by Prof. dr W.R. Hagen and Ir P.L. Hagedoorn. From November 1998 until December 1999 he was a member of the executive committee of Integrand Wageningen. In November 2000 he left Wageningen to perform a 7 months research project at the Department of Molecular Biology and Biotechnology, Krebs Institute for Biomolecular Research, University of Sheffield, England under supervision of Prof. dr D.W. Rice and Dr J. van der Oost. This yielded a second master thesis about the purification, crystallization and X-ray diffraction of three thermostable sugar converting enzymes. Following this, he started to assist the editors of the books

‘Economics of Sustainable Energy in Agriculture’ (November 2001-April 2002) and ‘Risk and Uncertainty in Environmental and Resource Economics’ (December 2002-May 2003). Meanwhile he earned his Master of Science degree in January 2003.

In November 2003 he started his PhD at Leiden University in the Biophysical Structural Chemistry department, headed by Prof. dr J.P.

Abrahams. His research focused on 3D structure determination of proteins employing X-ray crystallography and small-angle X-ray solution scattering.

Some results described in this thesis were produced as part of collaborations with the ETH (Zürich, Switzerland), the LUMC (Leiden, the Netherlands), the LMU (München, Germany), the Delft University of Technology (the Netherlands), the Netherlands Proteomics Center (Utrecht) and the CIB (Madrid, Spain).

As of April 2009 Daniël is employed as a Postdoc researcher on the disturbed heparan sulphate biosynthesis in osteochondroma. This research is a joint project of Leiden University and the LUMC.

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