University of Groningen
Bio-orthogonal metal catalysis
de Bruijn, Anne Dowine
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2018
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de Bruijn, A. D. (2018). Bio-orthogonal metal catalysis: For selective modification of dehydroalanine in
proteins and peptides. Rijksuniversiteit Groningen.
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Acknowledgements
122
I am writing this section moments after resigning from my thirteenth contract at the University
of Groningen. An odd accomplishment. Staying for so long clearly shows I had a really good time here. Writing these pages forms the end of an era; a great one; one which would have not been so great without the many people that I met and worked with during all this time. So thank you all for that.
Special thanks to Gerard. Het was min of meer toeval dat ik tijdens mijn bachelor in 2007 bij jou in de groep terecht kwam, omdat er gewoonweg geen andere organische 14-weeks-projecten meer waren in september. Maar het is zeker geen toeval dat ik ongeveer 10 jaar (!) bij je in de groep ben gebleven (minus mijn tweejarig Canadees avontuur). Ik vind je een bijzonder fijne supervisor, omdat je je studenten hun eigen gang laat gaan. Je geeft veel ruimte, maar bent er wanneer dat nodig is voor zowel chemische als persoonlijke issues. Bedankt voor alle ruimte, kansen, steun en vertrouwen die je me gegeven hebt. Ik ga je missen.
Secondly, I would like to thank the members of my reading committee: Adri Minnaard, Martin Witte and Nathaniel Martin for approving the thesis. Extra dank aan Martin, voor het ongelofelijk
gedetailleerde nakijken. Ik hoop dat alles wat cursief, vet gedrukt of subscript moet zijn, dat nu ook is.
Then I would like to thank my awesome paranymphs, Manu and Clemens. I cannot imagine a
better duo to accompany me into the aula. Manu you are my favourite colleague. Both because
of the great discussions and ideas we had about actual work, but even more for your great personality. Thank you for teaching me a tiny little fraction of Italian temper, thank you for the lovely conference trips, and thank you for always listening to my frustration whenever I arrived late in the office because of whatever total disaster happened that day. Clemens, thank you for
appearing in the Ruffles group. You are a great addition to the institute. I learned a lot from you, even though we did not work together on a project. Thanks for all the free advice you always give, whether I am asking for it or not :)
During my ten years in the Ruffles group there are many people that made this journey a lot of fun and much more endurable. Thank you Ana, Ivana, Manu (again), Katy, Annika and Lara for
being office buddies at some point in time. One might think an office with so many women would never lead to efficient research, but I think we all managed quite well. Thanks Cora, Zhi and Linda
for being my current office buddies. Sorry I was mostly anti-social, wearing my headphones while writing all the time. Jeffrey, bedankt voor het introduceren van ‘echte’ biochemie. Het bleek toch
minder eng dan gedacht. Liliana, thanks for all the times you functioned as my portable UV/vis
spectrometer to give confirmation if my solutions were still yellow, and thanks for always turning on Virgin Radio. A lab ain’t a lab senza musica rock. Ruben, bedankt voor de heerlijke sfeer op lab
201, zowel met als zonder Rammstein. Succes met de laatste loodjes. Nathalie, thanks for sharing a
bench at biochemistry with me. Arjan, bedankt voor het altijd prettig samenwerken en chemisch
sparren. Ik vind het heel leuk dat we weer collega’s worden! Sambika, thanks for all the HCCA
aliquots you once made. I still used one last week! Reinder, bedankt voor alle Dha-gerelateerde
discussies en bedankt voor je hulp met de NMR. Roos, bedankt dat je voor een project van mij
123 Acknowledgements
aan hoofdstuk 5 en ik weet zeker dat jij er nóg een hoofdstuk van gaat maken te zijner tijd. Ruben Feringa en Ruben Oudshoorn ook jullie bedankt voor de bijdragen aan het photocatalysis project.
Dan, Lise bedankt voor de samenwerking in het zwaartekracht programma. Michael Lerch, thanks
for the nice collaboration for the conference in Basel. It was a real pleasure working with you, and I learned a lot from it. And finally from the ‘old’ days, pre-PhD time: thank you Núria, and Tieme
for training me back then. I managed, which means you trained me well!
Then, of course, Wesley, thank you for never suspending me! Thanks Marta, for everything you
did for the FMS, for nominating me for Faces of Science, but mostly thank you for the ‘gezellige’ chats at any FMS related event. Marthe van Walvoort, bedankt voor het onder de aandacht brengen
van de Three Minute Thesis Competition. Ondanks dat ik vergelijkbare dingen heb gedaan, heb ik hier het meeste van geleerd. I also would like to thank Hanadi Sleiman. Although you did not
directly contribute to the research in this thesis, you know the time in your lab has taught me a lot and shaped me as the researcher I am today.
Theodora, bedankt voor het up- en running houden van de TQD en voor het feit dat we er altijd
zelf mee mogen spelen. TQD, thanks for (almost) never complaining if I’d set you up for hours and
hours of measurements again. You are my favourite apparatus, even though you are not made by . Johan, bedankt voor het operationeel maken van de oude MALDI. Pieter, bedankt voor het maken van de mooie LEDjes. Hoofdstuk 4 en 5 zijn er veel sneller mee tot stand gekomen.
Annette, bedankt voor alle administratieve ondersteuning. Tineke, bedankt voor alle gezellige
bijpraatmomentjes.
Furthermore thanks to everybody else at the Stratingh Institute. Thanks for the nice working
environment you all create together. I have only encountered nice people during these many years. Also thanks to all the people of biochemistry. I know I only appear downstairs once in a
while when I really cannot do without an ML-1 lab, but I feel totally comfortable in your labs now. Thanks as well for the nice daily lunch breaks. It is great to see how the relationship between up- and downstairs has changed over the years. Getting invited for the yearly lab-uitje felt as if our institutes had truly merged, which I think is the key to do even better science than we already conduct.
So people, thank you very much! After fifteen years at the RuG, I guess it is time to move on. It was awesome.
Jakob en Bart, lieve jongens, bedankt dat jullie er zijn. Zonder jullie was ik lang niet zo efficiënt!
En Bouk, je weet het. Zonder jou was me dit niet gelukt. Dan had ik óf opgegeven, óf had ik mezelf
in mijn enthousiasme compleet overwerkt. Dus dankjewel, voor alles, maar vooral voor keeping me sane.
