Towards an integrated psychoneurophysiological approach of irritable bowel syndrome
Veek, P.P.J. van der
Citation
Veek, P. P. J. van der. (2009, March 12). Towards an integrated
psychoneurophysiological approach of irritable bowel syndrome. Retrieved from https://hdl.handle.net/1887/13604
Version: Corrected Publisher’s Version
License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden
Downloaded from: https://hdl.handle.net/1887/13604
Note: To cite this publication please use the final published version (if
applicable).
TOWARDS AN INTEGRATED
PSYCHONEUROPHYSIOLOGICAL APPROACH OF IRRITABLE BOWEL SYNDROME
Patrick P.J. van der Veek
ISBN: 978-90-8559-489-8
© 2009 – P.P.J. van der Veek
Cover photo: Michael Slezak
Printed by Optima Grafische Communicatie, Rotterdam
No part of this thesis may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information stor- age and retrieval system, without permission in writing from the author.
The printing of this thesis was financially supported by: J.E. Jurriaanse Stichting, Ferring Pharmaceuticals, Astra Zeneca, Tramedico B.V., ABBOTT Immunology B.V., Zambon.
TOWARDS AN INTEGRATED
PSYCHONEUROPHYSIOLOGICAL APPROACH OF IRRITABLE BOWEL SYNDROME
Proefschrift
ter verkrijging van
de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof.mr. P.F. van der Heijden,
volgens besluit van het College voor Promoties te verdedigen op donderdag 12 maart 2009
klokke 13.45 uur
door
Patrick Petrus Johannes van der Veek geboren te Lisse in 1975
Promotiecommissie
Promotor: Prof. Dr. A.A.M. Masclee
Co-promotor: Dr. Y.R. van Rood
Referent: Dr. R.J.F. Felt-Bersma (VU Medisch Centrum, Amsterdam)
Overige leden: Prof. Dr. D.W. Hommes Prof. Dr. P. Spinhoven Prof. Dr. F.G. Zitman Dr. Ir. C.A. Swenne Dr. Ir. H.W. Verspaget
CONTENTS
Chapter 1 Introduction 7
Chapter 2 Viscerosensory-cardiovascular reflexes: altered baroreflex sensitivity in irritable bowel syndrome.
Am J Physiol Regul Integr Comp Physiol 2005;289:R970-6.
21
Chapter 3 Proximal and distal gut hormone secretion in irritable bowel syndrome.
Scand J Gastroenterol 2006;41:170-7.
39
Chapter 4 Role of Tumor Necrosis Factor-α and Interleukin-10 gene polymorphisms in irritable bowel syndrome.
Am J Gastroenterol 2005;100:2510-6.
55
Chapter 5 Recto-colonic reflex is impaired in patients with irritable bowel syndrome.
Neurogastroenterol Motil 2007;19:653-9.
69
Chapter 6 Symptom severity but not psychopathology predicts visceral hypersensitivity in irritable bowel syndrome.
Clin Gastroenterol Hepatol 2008;6:321-8.
85
Chapter 7 Short and long term benefit of relaxation training for irritable bowel syndrome.
Aliment Pharmacol Ther 2007;26:943-52.
103
Chapter 8 Testing a biobehavioral model of irritable bowel syndrome.
Submitted for publication.
121
Chapter 9 Summary and Discussion 139
Samenvatting en discussie 149
Nawoord 159
Curriculum vitae 161
Publications 163
