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New insight into device therapy for chronic heart failure

Ypenburg, C.

Citation

Ypenburg, C. (2008, October 30). New insight into device therapy for chronic heart failure. Retrieved from https://hdl.handle.net/1887/13210

Version: Corrected Publisher’s Version

License: Licence agreement concerning inclusion of doctoral thesis in the Institutional Repository of the University of Leiden

Downloaded from: https://hdl.handle.net/1887/13210

Note: To cite this publication please use the final published version (if

applicable).

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New insights into device therapy for chronic heart failure

Claudia Ypenburg

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The studies described in this thesis were performed at the department of Cardiology of the Leiden University Medical Center, Leiden, the Netherlands

Copyright © 2008 Claudia Ypenburg, Leiden, the Netherlands. All rights reserved. No part of this book may be reproduced or transmitted in any form or by any means, without prior written permission of the author

Lay out: Chris Bor, Amsterdam, the Netherlands

Printed by: Buijten & Schipperheijn, Amsterdam, the Netherlands ISBN: 978-90-9023388-8

Financial support to the costs associated with the publication of this thesis from Biotronik BV, Boehringer Ingelheim BV, Boston Scientific BV, Bristol-Meyers Squibb BV, Eli Lilly BV, GE Healthcare Medical Diagnostics, de J.E. Jurriaanse stichting, Medtronic BV, Merck Sharp &

Dohme BV, Novartis-Pharma BV, Pfizer BV, Sanofi-Aventis BV, Schering-Plough BV, Stichting EMEX, St. Jude Medical NL BV, Toshiba Medical Systems BV and Zambon NL BV is gratefully acknowledged.

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New insights into device therapy for chronic heart failure

PROEFSCHRIFT

ter verkrijging van

de graad van Doctor aan de Universiteit van Leiden, op gezag van Rector Magnificus prof. mr. P.F. van der Heijden,

volgens besluit van het College voor Promoties te verdedigen op donderdag 30 oktober 2008

klokke 15.00 uur

door

CLAUDIA YPENBURG

geboren te Amstelveen

1979

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PROMOTIECOMISSIE

Promotores: Prof. dr. J.J. Bax Prof. dr. M.J. Schalij

Referent: Prof. dr. J. Brugada (Hopital Clinic, Barcelona, Spanje)

Overige leden: Prof. dr. E.E. van der Wall Prof. dr. R.J. Klautz

Prof. dr. H.J. Wellens (Academisch Ziekenhuis Maastricht) Mw. dr. L. van Erven

Financial support by the Netherlands Heart Foundation and the Interuniversity Cardiology Institute of the Netherlands for the publication of this thesis is gratefully acknowledged.

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Voor David en Finn

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TABLE OF CONTENTS

Chapter 1 General introduction and outline of the thesis 9

PART I ISSUES BEFORE DEVICE IMPLANTATION

21

Chapter 2 Assessment of left ventricular dyssynchrony by speckle tracking strain imaging: comparison between longitudinal, circumferential and radial strain in cardiac resynchronization therapy patients

J Am Coll Cardiol 2008;51:1944-52

23

Chapter 3 Left ventricular resynchronization is mandatory for response to cardiac resynchronization therapy: analysis in patients with evidence of left ventricular dyssynchrony at baseline

Circulation 2007;116:1440-8

39

Chapter 4 Extent of viability to predict response to cardiac resynchronization therapy in ischemic heart failure patients

J Nucl Med 2006;47:1565-70

51

Chapter 5 Impact of viability and scar tissue on response to cardiac resynchronization therapy in ischemic heart failure patients

Eur Heart J 2006;28:33-41

63

Chapter 6 Effect of total scar burden on contrast-enhanced magnetic resonance imaging on response to cardiac resynchronization therapy

Am J Cardiol 2007;99:657-60

79

Chapter 7 Myocardial contractile reserve predicts improvement in left ventricular function after cardiac resynchronization therapy

Am Heart J 2007;154:1160-5

89

Chapter 8 Optimal left ventricular lead position predicts reverse remodeling and survival after cardiac resynchronization therapy

J Am Coll Cardiol 2008; in press

101

Chapter 9 Non-invasive imaging in cardiac resynchronization therapy – part 1:

selection of patients PACE 2008; in press

115

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PART II ISSUES AFTER DEVICE IMPLANTATION

151

Chapter 10 Long-term prognosis after cardiac resynchronization therapy is related to the extent of left ventricular reverse remodeling at mid-term follow-up Submitted

153

Chapter 11 Effects of interruption of long-term cardiac resynchronization therapy on left ventricular function and dyssynchrony

Am J Cardiol 2008; in press

167

Chapter 12 Changes in global left ventricular function in heart failure patients undergoing cardiac resynchronization therapy using novel automated function imaging

Submitted

177

Chapter 13 Acute effects of initiation and withdrawal of cardiac resynchronization therapy on papillary muscle dyssynchrony and mitral regurgitation J Am Coll Cardiol 2007;50:2071-7

191

Chapter 14 Mechanism of improvement in mitral regurgitation after cardiac resynchronization therapy

Eur Heart J 2008;29:757-65

205

Chapter 15 Benefit of combined resynchronization and defibrillator therapy in heart failure patients with and without ventricular arrhythmias

J Am Coll Cardiol 2006;48:464-70

221

Chapter 16 Intrathoracic impedance monitoring to predict decompensated heart failure

Am J Cardiol 2006;99:554-7

235

Chapter 17 Non-invasive imaging in cardiac resynchronization therapy – part 2:

follow-up and optimization of settings PACE 2008; in press

243

Summary, conclusions and future perspectives 265

Samenvatting, conclusies en toekomstperspectief 275

List of publications 283

Acknowledgements 287

Curiculum vitae 288

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