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Cover Page The handle http://hdl.handle.net/1887/38693 holds various files of this Leiden University dissertation. Author: Gvozdenovic, Emilia Title: Monitoring rheumatoid arthritis Issue Date: 2016-03-31

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Cover Page

The handle http://hdl.handle.net/1887/38693 holds various files of this Leiden University dissertation.

Author: Gvozdenovic, Emilia

Title: Monitoring rheumatoid arthritis Issue Date: 2016-03-31

(2)

Monitoring

Rheumatoid Arthritis

Emilia Gvozdenović

(3)

ISBN/EAN: 978-90-6464-980-6

The research presented in this thesis was performed at the department of Rheumatology at the Leiden University Medical Center, Leiden. This research was financially supported by Pfizer B.V., AbbVie and Roche.

© Emilia Gvozdenović 2016

No part of this thesis may be reproduced in any form without written permission from the author or, when appropriate, of the publishers of the publications.

Cover: Erwin Meijer

Lay-out: Ferdinand van Nispen

Printing: GVO drukkers & vormgevers B.V.

The publication of this thesis was financially supported by Pfizer B.V. and UCB Pharma B.V.

Monitoring

Rheumatoid Arthritis

Proefschrift

ter verkrijging van

de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof.mr. C.J.J.M. Stolker,

volgens besluit van het College voor Promoties te verdedigen op donderdag 31 maart 2016 klokke 11.15 uur

door

Emilia Gvozdenović

geboren te Drammen (Noorwegen) in 1987

(4)

ISBN/EAN: 978-90-6464-980-6

The research presented in this thesis was performed at the department of Rheumatology at the Leiden University Medical Center, Leiden. This research was financially supported by Pfizer B.V., AbbVie and Roche.

© Emilia Gvozdenović 2016

No part of this thesis may be reproduced in any form without written permission from the author or, when appropriate, of the publishers of the publications.

Cover: Erwin Meijer

Lay-out: Ferdinand van Nispen

Printing: GVO drukkers & vormgevers B.V.

The publication of this thesis was financially supported by Pfizer B.V. and UCB Pharma B.V.

Monitoring

Rheumatoid Arthritis

Proefschrift

ter verkrijging van

de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof.mr. C.J.J.M. Stolker,

volgens besluit van het College voor Promoties te verdedigen op donderdag 31 maart 2016 klokke 11.15 uur

door

Emilia Gvozdenović

geboren te Drammen (Noorwegen) in 1987

(5)

Promotores

Prof. dr. D.M.F.M. van der Heijde

Prof. dr. R.B.M. Landewé (AMC - UvA, Amsterdam) Copromotor

dr. C.F. Allaart

Leden Promotiecommissie Prof. dr. G. Kloppenburg

Prof. dr. P.L.C.M.Van Riel (RadboudUMC, Nijmegen) Prof. dr. D. van Schaardenburg (AMC-UvA, Amsterdam) Prof. dr. R. Brand

Prof. dr. R.G.H.H. Nelissen

CONTENTS

Chapter 1 General introduction 7

Chapter 2 Comparison of characteristics of international and national 25 databases in rheumatoid arthritis: a systematic literature

review

Chapter 3 Intra articular injection with corticosteroids in patients with 55 recent onset rheumatoid arthritis: subanalyses from the BeSt

study

Chapter 4 Assessment of global disease activity in RA patients monitored 69 in the METEOR database: The patient’s versus the

rheumatologist’s opinion

Chapter 5 Assessment of global disease activity in RA by patients and 83 physicians: differences across countries in the METEOR

database

Chapter 6 DAS steered therapy in clinical practice; cross-sectional results 99 from the METEOR database

Chapter 7 Does reporting to follow a guideline imply that this guideline 115 is really applied in clinical practice? The International

Recommendation Implementation Study (IRIS)

Chapter 8 Summary and general conclusion 133

Chapter 9 Nederlandse samenvatting 143

List of publications 151

Curriculum Vitae 152

Dankwoord 153

(6)

Promotores

Prof. dr. D.M.F.M. van der Heijde

Prof. dr. R.B.M. Landewé (AMC - UvA, Amsterdam) Copromotor

dr. C.F. Allaart

Leden Promotiecommissie Prof. dr. G. Kloppenburg

Prof. dr. P.L.C.M.Van Riel (RadboudUMC, Nijmegen) Prof. dr. D. van Schaardenburg (AMC-UvA, Amsterdam) Prof. dr. R. Brand

Prof. dr. R.G.H.H. Nelissen

CONTENTS

Chapter 1 General introduction 7

Chapter 2 Comparison of characteristics of international and national 25 databases in rheumatoid arthritis: a systematic literature

review

Chapter 3 Intra articular injection with corticosteroids in patients with 55 recent onset rheumatoid arthritis: subanalyses from the BeSt

study

Chapter 4 Assessment of global disease activity in RA patients monitored 69 in the METEOR database: The patient’s versus the

rheumatologist’s opinion

Chapter 5 Assessment of global disease activity in RA by patients and 83 physicians: differences across countries in the METEOR

database

Chapter 6 DAS steered therapy in clinical practice; cross-sectional results 99 from the METEOR database

Chapter 7 Does reporting to follow a guideline imply that this guideline 115 is really applied in clinical practice? The International

Recommendation Implementation Study (IRIS)

Chapter 8 Summary and general conclusion 133

Chapter 9 Nederlandse samenvatting 143

List of publications 151

Curriculum Vitae 152

Dankwoord 153

(7)

Chapter 1

General introduction

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