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Enzymology and regulation of the atropine metabolism in pseudomonas

putida

Stevens, W.F.

Citation

Stevens, W. F. (1969, June 18). Enzymology and regulation of the atropine metabolism in

pseudomonas putida. Retrieved from https://hdl.handle.net/1887/77056

Version:

Not Applicable (or Unknown)

License:

Leiden University Non-exclusive license

Downloaded from:

https://hdl.handle.net/1887/77056

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Cover Page

The handle

http://hdl.handle.net/1887/77056

holds various files of this Leiden University

dissertation.

Author: Stevens, W.F.

Title: Enzymology and regulation of the atropine metabolism in pseudomonas putida

Issue Date: 1969-06-18

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ENZYMOLOGY AND REGULATION OF

THE ATROPINE METABOLISM IN

PSEUDOMONAS PUTIDA

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ENZYMOLOGY AND REGULATION OF THE

ATROPINE METABOLISM IN

PSEUDOMONAS PUTIDA

PhD THESIS

TO OBTAIN THE DEGREE OF DOCTOR IN MATHEMATICS

AND SCIENCE AT THE STATE UNIVERSITY LEIDEN,

ON THE AUTHORITY OF THE RECTOR MAGNIFICUS

DR L. KUKENHEIM Ezn, PROFESSOR IN THE FACULTY OF

LANGUAGE AND LITERATURE, IN THE PRESENCE OF A COMMITTEE OF THE

SENATE, TO DEFEND ON WEDNESDAY

18 JUNE 1969 EXACTLY ON THE STROKE OF 16.45

BY

WILLEM FRANS STEVENS

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PROMOTOR: PROF. DR. A. RöRSCH

This thesis was written in the Dutch Language in 1969 and at that time deposited in the Repositorium of the Library of the Technical University, Delft, The Netherlands htpps://repository.tudelft.nl/view/tno; # 268336.

Only in 2019 the thesis was translated by the author in English as precise copy nearly page by page of the 1969 version (no update) and deposited at the same Library under nr htpps://repository.tudelft.nl/view/tno; #

The English translation is only meant to disseminate the scientific data, described in the Dutch version. It does not intend to add any new data. In case of differences in the interpretation of the intellectual property only the Dutch version counts.

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Dedicated to

my parents

Yvonne

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The thesis started off with the Homer-like poem in hexameter below. It is an explanation of the aim of this thesis. Atropos, as fate goddess on the Olympus, had the task to cut randomly the life-lines of the mortals with a pair of scissors. And as extract of Belladonna, she determined the fate of the new couple: by widening woman’s eye: she was almost blind, he dazzled, so both made the wrong choice.

What will happen to You, now Hades’ imperium has released a bacterium which contains an enzyme that will cut your life line?

Atropos in bronze,

by Peter Hoogerwerf

Atropos, gij waart godin van het noodlot en vrees’lijke rampspoed.

Gij waart bij machte ten gronde te richten, gij had een onzalige invloed

Door tot de Vader van Goden en Mensen het onheil te fluist’ren

Hiermee de sterv’ling voorgoed aan zijn blinde bestemming te kluist’ren

En als extract van bell’dona verwijdend het oog der beminde

Zodat gij aanstaande man alswel vrouw in hun keuze verblindde,

Welk lot brengt U een bacil die uit Hades’ rijk vrij is gegeven

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