Adoptive immunotherapy after HLA mismatched stem cell
transplantation
Oosten, L.E.M.
Citation
Oosten, L. E. M. (2007, November 21). Adoptive immunotherapy after HLA
mismatched stem cell transplantation. Retrieved from
https://hdl.handle.net/1887/12446
Version: Corrected Publisher’s Version
License: Licence agreement concerning inclusion of doctoral
thesis in the Institutional Repository of the University
of Leiden
Downloaded from: https://hdl.handle.net/1887/12446
Note: To cite this publication please use the final published version (if
applicable).
Contents
Chapter 1:
General introduction 7
Chapter 2:
Artifi cial antigen-presenting constructs effi ciently stimulate minor 35 histocompatibility antigen-specifi c cytotoxic T lymphocytes
Chapter 3:
TAP-inhibiting proteins US6, ICP47, and UL49.5 affect target cell 45 recognition by minor histocompatibility antigen-specifi c and
alloHLA-specifi c cytotoxic T lymphocytes
Chapter 4:
Investigation of peptide involvement in T cell allorecognition using 61 recombinant HLA class I multimers
Chapter 5:
Promiscuity of the alloHLA-A2-restricted T cell repertoire hampers 81 the generation of minor histocompatibility antigen-specifi c cytotoxic
T cells across HLA barriers
Chapter 6:
General discussion 101
Summary 123
Nederlandse samenvatting voor niet-immunologen 129
Abbreviations 139
Curriculum Vitae 141