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The handle http://hdl.handle.net/1887/33616 holds various files of this Leiden University dissertation.
Author: Kröner, Eleanore Sophie Jeanine
Title: Magnetic resonance imaging of vessel wall morphology and function
Issue Date: 2015-06-24
Magnetic Resonance iMaging of Vessel Wall MoRphology and function
Eleanore Sophie Jeanine Kröner
The research described in this thesis was carried out at the Departments of Cardiology (Head: Prof. dr. M.J. Schalij) and Radiology (Head: Prof. dr. M.A. van Buchem) of the Leiden University Medical Center.
The author of this thesis was financially supported by the Interuniversity Cardiology Institute of the Netherlands.
The research described in this thesis was supported by a grant of the Dutch Heart Foun- dation (Project 2006B138).
Additional financial support to the costs associated with the publication of this thesis from:
Toshiba Medical Systems Nederland is gratefully acknowledged.
Layout and Printing: Optima Grafische Communicatie (www.ogc.nl)
Magnetic Resonance iMaging of Vessel Wall MoRphology and function
pRoefschRift
ter verkrijging van
de graad van Doctor aan de Universiteit Leiden, op gezag van Rector Magnificus prof. mr. C.J.J.M. Stolker,
volgens besluit van het College voor Promoties te verdedigen op woensdag 24 juni 2015
klokke 11.15 uur door
Eleanore Sophie Jeanine Kröner geboren te Rotterdam in 1985
PROMOTIECOMMISSIE
Promotores: Prof. Dr. H.J. Lamb Prof. Dr. E.E. van der Wall Copromotor: Dr. H.J. Siebelink Overige leden: Prof. Dr. A.F. Cohen
Prof. Dr. B.J.M. Mulder (Academisch Medisch Centrum, Amsterdam) Prof. Dr. A. de Roos
Prof. Dr. A.C. van Rossum (Vrije Universiteit, Amsterdam) Prof. Dr. M.J. Schalij
Dr. A.J.H.A. Scholte Prof. Dr. A.G. Webb Dr. J.J.M. Westenberg
TABLE OF CONTENTS
Chapter 1. General introduction and outline 9
Part I: Imaging of vessel wall morphology
Chapter 2. High field carotid vessel wall imaging: a study on reproducibility Eur J Radiol 2013;82:680-5.
21
Chapter 3. Ultrahigh-field 7-T magnetic resonance carotid vessel wall imaging: initial experience in comparison with 3-T field strength Invest Radiol 2012;47:697-704.
35
Part II: Imaging of vessel wall function
Chapter 4. Evaluation of sampling density on the accuracy of aortic pulse wave velocity from velocity-encoded MRI in patients with marfan syndrome
J Magn Reson Imaging 2012;36:1470-6.
55
Chapter 5. MRI-assessed regional pulse wave velocity for predicting absence of regional aorta luminal growth in marfan syndrome Int J Cardiol 2013;167:2977-82.
67
Chapter 6. Coupling between MRI-assessed regional aortic pulse wave velocity and diameters in patients with thoracic aortic aneurysm Neth Heart J 2015; in press
83
Chapter 7. Pulse wave velocity and flow in the carotid artery versus the aortic arch: effects of aging
J Magn Reson Imaging 2014;40:287-93.
97
Part III: Imaging of vessel wall morphology and function
Chapter 8. Coupling of vessel wall morphology and function in the aorta and the carotid artery: an evaluation with MRI
Int J Cardiovasc Imaging 2014;30:91-8.
111
Chapter 9. Morphological and functional carotid vessel wall properties in relation to cerebral white matter lesions in myocardial infarction patients
Neth Heart J 2015; in press
125
Chapter 10. Summary and Conclusions 137
Samenvatting en Conclusies 143
List of Publications 151
Dankwoord 153
Curriculum Vitae 155
