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University of Groningen Acute abdominal pain in children Timmerman, Marjolijn Engelina Willemijn

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University of Groningen

Acute abdominal pain in children

Timmerman, Marjolijn Engelina Willemijn

IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from

it. Please check the document version below.

Document Version

Publisher's PDF, also known as Version of record

Publication date:

2019

Link to publication in University of Groningen/UMCG research database

Citation for published version (APA):

Timmerman, M. E. W. (2019). Acute abdominal pain in children. Rijksuniversiteit Groningen.

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Downloaded from the University of Groningen/UMCG research database (Pure): http://www.rug.nl/research/portal. For technical reasons the number of authors shown on this cover page is limited to 10 maximum.

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Acute abdominal pain

in children

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ISBN 978-94-028-1579-5 Cover photo Bill White

Cover design Marjolijn Timmerman Lay-out Marjolijn Timmerman Printed by IPSKAMP printing

Publication of this thesis was financialy supported by the Junior Scientific Mas-terclass, the Graduate School of Medical Sciences, the University of Groningen and the University Medical Center Groningen.

© 2019 Marjolijn E.W. Timmerman

All rights reserved. No part of this thesis may be reproduced or transmitted, in any form or by any means, without permission of the author.

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Acute abdominal pain in children

Proefschrift

ter verkrijging van de graad van doctor aan de Rijksuniversiteit Groningen

op gezag van de

rector magnificus prof. dr. E. Sterken en volgens besluit van het College voor Promoties.

De openbare verdediging zal plaatsvinden op maandag 8 juli 2019 om 12.45 uur

door

Marjolijn Engelina Willemijn Timmerman

geboren op 1 februari 1993 te Amersfoort

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Promotor Prof. dr. E. Heineman Copromotor Dr. P.M.A. Broens Beoordelingscommissie Prof. dr. H.J. Verkade Prof. dr. J.B.F. Hulscher Prof. dr. M.A. Benninga

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Paranimfen

Dhr. M.F. Boekel

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Table of contents

Chapter 1.

General introduction

11

Chapter 2.

The influence of underweight and obesity on the diagnosis and treatment of appendicitis in children

Int J Colorectal Dis. 2016; 31: 1467–1473.

25

Chapter 3.

Cytomegalovirus and human herpesvirus 6 in the development of acute appendicitis in children

Submitted.

41

Chapter 4.

Using laxatives and/or enemas to accelerate the diagnosis in chil-dren presenting with acute abdominal pain: a randomised con-trolled trial study protocol

BMJ Paediatrics Open 2018;2:e000341.

51

Chapter 5.

The problem of defecation disorders in children is underestimated and easily goes unrecognized: a cross-sectional study

Eur J Pediatr. 2018 Sep 27.

65

Chapter 6.

Prevalence of defecation disorders and their symptoms is compa-rable in children and young adults: a cross-sectional study

Submitted.

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Chapter 7.

Reproducibility, feasibility and validity of the Groningen Defecation and Fecal Continence questionnaires.

Scand J Gastroenterol. 2018 Jun-Jul;53(7):790-796.

95

Chapter 8.

Discussion and future perspective

113 Chapter 9. Summary 125 Chapter 10. Samenvatting 131 Chapter 11. Appendix 137

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