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Plasmacytoid dendritic cells: how to control the good, the bad, and the ugly at the molecular level - Table of contents

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UvA-DARE is a service provided by the library of the University of Amsterdam (https://dare.uva.nl)

UvA-DARE (Digital Academic Repository)

Plasmacytoid dendritic cells: how to control the good, the bad, and the ugly at

the molecular level

Karrich, J.J.

Publication date

2013

Link to publication

Citation for published version (APA):

Karrich, J. J. (2013). Plasmacytoid dendritic cells: how to control the good, the bad, and the

ugly at the molecular level.

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table of contents

Chapter 1 General Introduction 9 Chapter 2 The transcription factor Spi-B regulates human

plasmacytoid dendritic cell survival through direct

induction of the anti-apoptotic gene BCL2A1 37 Chapter 3 microRNA-146a regulates survival and maturation

of human plasmacytoid dendritic cells 65 Chapter 4 microRNA-491 regulates Spi-B expression

in plasmacytoid dendritic cells 85 Chapter 5 Direct interaction between the Ets transcription

factor Spi-B and NF-κB subunits regulates

plasmacytoid dendritic cell activation and survival 101 Chapter 6 The transcriptional regulator NAB2 reveals a two-step

induction of TRAIL in activated plasmacytoid DCs 121 Chapter 7 IL-21 stimulated human plasmacytoid dendritic

cells secrete Granzyme B, which impairs their

capacity to induce T cell proliferation 147 Chapter 8 General Discussion 167

Addendum 183

Summary 185

Samenvatting 187

Dankwoord 189

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