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Plasmacytoid dendritic cells: how to control the good, the bad, and the ugly at
the molecular level
Karrich, J.J.
Publication date
2013
Link to publication
Citation for published version (APA):
Karrich, J. J. (2013). Plasmacytoid dendritic cells: how to control the good, the bad, and the
ugly at the molecular level.
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table of contents
Chapter 1 General Introduction 9 Chapter 2 The transcription factor Spi-B regulates human
plasmacytoid dendritic cell survival through direct
induction of the anti-apoptotic gene BCL2A1 37 Chapter 3 microRNA-146a regulates survival and maturation
of human plasmacytoid dendritic cells 65 Chapter 4 microRNA-491 regulates Spi-B expression
in plasmacytoid dendritic cells 85 Chapter 5 Direct interaction between the Ets transcription
factor Spi-B and NF-κB subunits regulates
plasmacytoid dendritic cell activation and survival 101 Chapter 6 The transcriptional regulator NAB2 reveals a two-step
induction of TRAIL in activated plasmacytoid DCs 121 Chapter 7 IL-21 stimulated human plasmacytoid dendritic
cells secrete Granzyme B, which impairs their
capacity to induce T cell proliferation 147 Chapter 8 General Discussion 167
Addendum 183
Summary 185
Samenvatting 187
Dankwoord 189