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Dermal absorption of chemicals through normal and compromised skin

Jakasa, I.

Publication date

2006

Link to publication

Citation for published version (APA):

Jakasa, I. (2006). Dermal absorption of chemicals through normal and compromised skin.

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Stellingen

behorende bij het proefschrift

"Dermal absorption of chemicals through normal and compromised skin"

1. The value and necessity of in vivo studies outweigh their laboriousness

and price (this thesis)

2. Use of dermal absorption data of neat chemicals to predict the risk of

dermal exposure to mixtures, as usual in current risk assessment, will result in wrong conclusions (this thesis)

3. "Is there anything that the skin can't do? In short, the question is

impossible to answer in any condensed form. Besides, we live in many skins, from head to foot" (Albert M. Kligman. In: What is the true function

of skin? Experimental Dermatology 2002:11-159-180)

4. The measurement of dermal exposure has many uncertainties , therefore

biological monitoring when available should be the method of choice for the assessment cf health risk of workers (this thesis)

5. Proper barrier function of normal looking skin should not be taken for

granted (this thesis)

6. The more permeable skin is, the more susceptible it is to local effects of

chemicals (this thesis)

7. "The need for accuracy must be weighted against the need for finality"

(Comments by the Justices of the U.S. Supreme Court bringing to a close the uncertain outcome one month after U.S. Presidential elections in 2000 between G. W. Bush and A. Gore)

8. The "Inburgeringcursus" should start with: How to keep your "fiets" from

being stolen

9. In pursuing the scientific career, one has to be prepared to live with

suitcases in his/her hand

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