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RNA splicing in the heart
Changing parts and performance
van den Hoogenhof, M.M.G.
Publication date
2018
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Citation for published version (APA):
van den Hoogenhof, M. M. G. (2018). RNA splicing in the heart: Changing parts and
performance.
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516079-L-st-hoogenhof 516079-L-st-hoogenhof 516079-L-st-hoogenhof 516079-L-st-hoogenhof Processed on: 7-2-2018 Processed on: 7-2-2018 Processed on: 7-2-2018 Processed on: 7-2-2018
Propositions accompanying the thesis / Stellingen behorend bij het proefschrift:
RNA splicing in the heart
RNA splicing in the heart
changing parts and performance
changing parts and performance
Maarten van den HoogenhofMaarten van den Hoogenhof
1. Loss of RBM20 is pro-arrhythmic.
Verlies van RBM20 is pro-arrhythmisch. (Dit(Dit proefschrift)
2. Although circular RNAs that arise from the Titin gene are mainly mediated by alternative Although circular RNAs that arise from the Titin gene are mainly mediated by alternative splicing of the linear transcript, this is not a general feature of circular RNAs.
splicing of the linear transcript, this is not a general feature of circular RNAs.
Ondanks dat circulaire RNAs die ontstaanontstaan uit het Titine gen voornamelijk gevormd worden door alternatieve splicing van het lineairelineaire transcript, is dit niet een algemene eigenschap van circulaire RNAs. (Dit proefschrift)
3. Advances in next-generation sequencing technologies are and will be the driving force Advances in next-generation sequencing technologies are and will be the driving force behind expanding our knowledge about alternative splicing.
behind expanding our knowledge about alternative splicing.
Vooruitgang in next-generation sequencingsequencing technologieën is en zal de drijvende kracht achter het uitbreiden van ons begrip van alternatievealternatieve splicing zijn. (Dit proefschrift)
4. The indifference of capitalism is a much greater threat than any terrorist organization.The indifference of capitalism is a much greater threat than any terrorist organization.
De onverschilligheid van het kapitalismekapitalisme is een veel groter gevaar dan elke terroristische organizatie. (Vrij naar Yuval Noah Harari)Harari)
5. Too many people, scientists included, think that science is not (supposed to be) fun.Too many people, scientists included, think that science is not (supposed to be) fun.
Teveel mensen, wetenschappers inclusief,inclusief, denken dat wetenschap niet leuk is (of hoort te zijn).
6. Every system will focus on exactly that, by which its success is measured.Every system will focus on exactly that, by which its success is measured.
Een systeem richt zich altijd daarnaar, waarwaar het succes van dat systeem aan gemeten wordt.
7. A society based on trust is not only happier, but also more efficient and cheaper. A society based on trust is not only happier, but also more efficient and cheaper.
Een maatschappij gebaseerd op vertrouwenvertrouwen is niet alleen gelukkiger, maar ook efficienter en goedkoper.(Vrij naar Rutger Bregman)
8. The 1969 Ford Mustang Boss 429 is the best car ever built.The 1969 Ford Mustang Boss 429 is the best car ever built.
