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UvA-DARE is a service provided by the library of the University of Amsterdam (https://dare.uva.nl)

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Therapeutic arteriogenesis: from experimental observations towards clinical

application [cum laude]

van Royen, N.

Publication date

2003

Link to publication

Citation for published version (APA):

van Royen, N. (2003). Therapeutic arteriogenesis: from experimental observations towards

clinical application [cum laude].

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CONTENTS

Chapter 1 11 Introduction and outline (published in part: Journal of Nuclear Cardiology

8:687-693)

Chapter 2 25 Stimulation of arteriogenesis; a new concept for the treatment of arterial occlusive

disease (Cardiovascular Rescarch:49(3), 543-553)

Chapter 3 49 Direct evidence for TNF-alpha signaling in arteriogenesis in the mouse hindlimb

(Circulation 105(14): 1639-41)

Chapter 4 57 CD44 mediates collateral artery development (submitted for publication)

Chapter 5 75 Time course of arteriogenesis following femoral artery occlusion (Cardiovascular

Research 49(3): 609-617)

Chapter 6 9J. GM-CSF a strong arteriogcnic factor acting by amplification of monocyte function

(Atherosclerosis 159:343-356)

Chapter 7 LÜ Exogenous application of Transforming Growth Factor-beta 1 stimulates

arteriogenesis in the peripheral circulation (the FASEB Journal 16(3):432-434)

Chapter 8 [33 Invasive and non-invasive evaluation of spontaneous arteriogenesis in a novel

porcine model for peripheral atherosclerotic obstructive disease. (Atherosclerosis 167(l):33-43)

Chapter 9 H i Modulation of collateral artery growth in a novel porcine hindlimb ligation model

using MCP-1. (American Journal ofPhysiology284(4):H1422-H1428)

Chapter 10 L67 Effects of local MCP-1 protein therapy on the development of the collateral

circulation and atherosclerosis in Watanabe hyperlipidemic rabbits. (Cardiovascular Research 57(1): 178-185)

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CONTEVIS

Chapter 11 183 Local Monocyte Chemoattractant Protein-1 therapy increases collateral artery

formation in ApoE mice but induces systemic monocytic CD1 lb expression, ncointima formation and plaque progression. (Circulation Research 92(2):218-25y

Chapter 12 203 Design of the START-trial. Stimulation of arteriogenesis using subcutaneous

application of GM-CSF as a new treatment for peripheral vascular disease. A randomized, double-blind and placebo-controlled study (submitted for publication) Chapter 1 3

Summary and conclusions Chapter 14 Samenvatting en conclusies Dankwoord Curriculum Vitae 217 223 229 235 List of Publications 237

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