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Characterization of the Myc collaborating oncogenes Bmi1 and Gfi1
Scheijen, G.P.H.
Publication date
2001
Link to publication
Citation for published version (APA):
Scheijen, G. P. H. (2001). Characterization of the Myc collaborating oncogenes Bmi1 and
Gfi1.
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Contents
Chapter 1
Chapter 2
Chapter 3
Chapter 4
Chapter 5
Chapter 6
Chapter 7
Chapter 8
Summary
Samenvatting
Abbreviations
Publications
Curriculum Vitae
IntroductionCharacterization of pal-J, a common proviral insertion site in murine leukemia virus-induced lymphomas of c-myc and pim-1 transgenic mice
Retroviral insertions in the blal locus result in long-range activation of the bmil proto-oncogene in B cell lymphomas
Bmi-1 collaborates with c-Myc in tumorigenesis by inhibiting c-Myc-induced apoptosis via INK4a/ARF
Gfil promotes thymocyte selection at different stages and inhibits death by neglect, during negative selection and in common receptor y-chain deficient mice
Chronic Myeloid Leukemia-like syndrome and lymphoblastic T cell tumors in mice transgenic for the transcription factor Gfi 1
Enforced expression of Gfi 1 alters craniofacial and tooth morphogenesis and induces osteoblastic neural crest cell tumors
E\i-myc and gfi J collaborate in T cell lymphomagenesis by targeting
a p53- and Bcl-2-independent apoptosis pathway
