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UvA-DARE is a service provided by the library of the University of Amsterdam (https://dare.uva.nl)

UvA-DARE (Digital Academic Repository)

Epidemiological studies on tuberculosis control and respiratory viruses

Sloot, R.

Publication date

2015

Document Version

Final published version

Link to publication

Citation for published version (APA):

Sloot, R. (2015). Epidemiological studies on tuberculosis control and respiratory viruses.

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33245 Sloot.qxp_cover 21-04-15 12:42 Pagina 1

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Epidemiological studies on tuberculosis control

and respiratory viruses

Rosa Sloot

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Epidemiological studies on tuberculosis control and respiratory viruses Thesis, University of Amsterdam (UvA), the Netherlands

ISBN: 978-90-6464-866-3 http://dare.uva.nl/dissertaties

Cover: image by P. Nijenhuis (modified by P. Duijn)

Lay-out: Ferdinand van Nispen, Citroenvlinder-dtp.nl, Bilthoven, the Netherlands

Printed by: GVO drukkers & vormgevers, Ede, the Netherlands Financial support for printing of this thesis was provided by:

KNCV Tuberculosis Foundation, AMC, Stichting tot Bevordering van de Klinische Epidemiologie Amsterdam, Delft Imaging Systems.

© 2015 Rosa Sloot, Amsterdam, the Netherlands

Published articles were reprinted with permission from the publishers. No part of this thesis may be reproduced, stored or transmitted without the prior permission of the author or, when appropriate, the publishers of the articles.

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Epidemiological studies on tuberculosis control

and respiratory viruses

ACADEMISCH PROEFSCHRIFT

ter verkrijging van de graad van doctor aan de Universiteit van Amsterdam

op gezag van de Rector Magnificus prof. dr. D.C. van den Boom

ten overstaan van een door het College voor Promoties ingestelde commissie, in het openbaar te verdedigen in de Agnietenkapel

op woensdag 10 juni 2015, te 10:00 uur

door Rosa Sloot geboren te Haarlem

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Promotiecommissie:

Promotores: Prof. dr. M.W. Borgdorff Universiteit van Amsterdam Prof. dr. M.D. de Jong Universiteit van Amsterdam Co-promotor: Dr. M.F. Schim van der Loeff Universiteit van Amsterdam Overige leden: Prof. dr. M.P. Grobusch Universiteit van Amsterdam Prof. dr. T. van der Poll Universiteit van Amsterdam Prof. dr. F.G.J. Cobelens Universiteit van Amsterdam Prof. dr. J.H. Richardus Erasmus Universiteit Rotterdam Prof. dr. D. van Soolingen Radboud Universiteit Nijmegen Dr. S. van den Hof KNCV Tuberculosefonds Faculteit der Geneeskunde

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Contents

Chapter 1 Introduction 7

Chapter 2 Clustering of tuberculosis cases based on variable-number tandem-repeat typing in relation to the population structure of Mycobacterium tuberculosis in the Netherlands.

J Clin Microbiol 2013;51:2427-31

19

Chapter 3 Yield of tuberculosis contact investigations in Amsterdam: opportunities for improvement.

Eur Respir J 2014;44:714-24

33

Chapter 4 Risk of tuberculosis after recent exposure: a 10-year follow-up study of contacts in Amsterdam.

Am J Respir Crit Care Med 2014;190:1044-52

53

Chapter 5 Biomarkers can identify pulmonary tuberculosis in HIV-infected drug users months prior to clinical diagnosis.

EBioMedicine 2015;2:172-9

73

Chapter 6 Distribution and viral load of respiratory viruses differ by illness severity in adults: a comparison between community and hospital populations.

In preparation

93

Chapter 7 General Discussion 119

Chapter 8 Summary 133

Samenvatting Dankwoord About the author Portfolio

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