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Cell-derived microparticles : composition and function
Biró, É.
Publication date
2008
Link to publication
Citation for published version (APA):
Biró, É. (2008). Cell-derived microparticles : composition and function.
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Stellingen bij het proefschrift
ell-derived microparticles
om
C
C
position and function
1. The lipid composition of platelet-derived microparticles is between that of platelet plasma- and granule membranes, suggesting that the microparticle membranes are a composite of platelet plasma- and granule membranes. – This thesis.
2. The lipid and antigenic composition of platelet- and endothelial cell-derived microparticles depends on the stimulus inducing their formation. – This
thesis.
3. Cell-derived microparticles promote thrombus formation in vivo in a tissue factor-dependent manner. – This thesis.
4. The percentages of platelet-derived microparticles exposing P-selectin and CD63 reflect the platelet activation status better than the total numbers of platelet-derived microparticles. – This thesis.
5. Ex vivo experiments support the role of microparticles in complement activation in vivo. – This thesis.
6. Retransfusion of pericardial blood does not contribute to systemic complement activation in patients undergoing cardiac surgery with cardiopulmonary bypass. – This thesis.
7. Laboratory tests of resistance to aspirin or adenosine diphosphate receptor antagonists are useless for the individual patient. – Alan D. Michelson, 54th
Annual Meeting of the Scientific and Standardization Committee of the ISTH, 2008, Vienna, Austria.
8. Measurements of thromboxane B2 (and its metabolites) in serum versus urine
provide information about different aspects of platelet function. – Garret A.
FitzGerald et al. Circulation 1983; 67: 1174-1177.
9. Measurements of vascular endothelial growth factor in serum do not reflect the circulating bioactive fraction. – Robert Möhle et al. Proc. Natl. Acad. Sci.
10. A close interaction between the physician, pharmacologist and clinical chemist is needed for the correct interpretation of the laboratory results of patients.
11. Sometimes when I consider what tremendous consequences come from little things … I am tempted to think there are no little things. – Bruce Barton. 12. Research is to see what everybody else has seen, and to think what nobody
else has thought. – Albert Szent-Györgyi.
13. Beter een zere vinger in de mond dan een pleister op de wond. – René
Berckmans.
14. Anyone who says sunshine brings happiness has never danced in the rain. –
Author unknown.
