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Inflammation and epilepsy: the contribution of astrocytes
Zurolo, E.
Publication date
2013
Link to publication
Citation for published version (APA):
Zurolo, E. (2013). Inflammation and epilepsy: the contribution of astrocytes.
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Contents:
Chapter 1:
Introduction
1.1 General introduction 10
1.2 Astrocytes immune response in epilepsy 30
1.3 Aim and outline 56
Chapter 2:
Inflammatory pathways and epilepsy
2.1 Tissue plasminogen activator and urokinase plasminogen 60 activator in human epileptogenic pathologies.
2.2 Evaluation of the innate and adaptive immunity in type I and 87 type II focal cortical dysplasias.
2.3 Activation of Toll-like receptor, RAGE and HMGB1 signalling 106 in malformations of cortical development.
2.4 The inflammatory molecules IL-1β and HMGB1 can rapidly 136 enhance focal seizure generation in rat entorhinal cortex
2.5 Regulation of Kir4.1 expression in astrocytes and astrocytic 148 tumors: a role for IL-1β
Chapter 3:
Regulation of inflammation in astrocytes: the role of miR 146a
3.1 Expression pattern of miR-146a, an inflammation-associated 177 microRNA, in experimental and human temporal lobe epilepsy.
3.2 MicroRNA-146a: a key regulator of astrocyte-mediated 193 inflammatory response
Chapter 4:
Astrocytes mediated signaling and epilepsy
4.1 CB1 and CB2 cannabinoid receptor expression during 217 development and in epileptogenic developmental pathologies.
4.2 Upregulation of adenosine kinase in astrocytes in experimental 241 and human temporal lobe epilepsy.
4.3 Overexpression of ADK in human astrocytic tumors and 260 peritumoral tissue is related to tumor-associated epilepsy.
Chapter 5:
General Discussion, Summary, Curriculum vitae 277
