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Development of simplified molecular tools for the diagnosis of kinetoplast
diseases
Mugasa, C.M.
Publication date
2010
Link to publication
Citation for published version (APA):
Mugasa, C. M. (2010). Development of simplified molecular tools for the diagnosis of
kinetoplast diseases.
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Contents
Chapter 1: Introduction 7
Chapter 2: Detection of Trypanosoma brucei parasites in blood
samples using real-time nucleic acid sequence-based amplification 37
Chapter 3: Nucleic acid sequence-based amplification with
oligochromatography for detection of Trypanosoma brucei in clinical
samples 49
Chapter 4: Simplified molecular detection of Leishmania parasites
in various clinical samples from patients with Leishmaniasis 65
Chapter 5: Accordance and concordance of PCR and NASBA followed
by olichochromotagraphy for the molecular diagnosis of Trypanosoma
brucei and Leishmania 75
Chapter 6: Phase II evaluation of sensitivity and specificity of PCR and
NASBA followed by oligochromatography for diagnosis of human African
trypanosomiasis in D.R. Congo and Uganda 85
Chapter 7: Diagnostic accuracy of molecular amplification tests for
Human African Trypanosomiasis – A systematic review 97
Summary / Samenvatting 118