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Properties of human antibodies to factor VIII defined by phage display
van den Brink, E.N.
Publication date
2000
Link to publication
Citation for published version (APA):
van den Brink, E. N. (2000). Properties of human antibodies to factor VIII defined by phage
display.
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Contents Chapter 1. Chapter 2. Chapter 3. Chapter 4. Chapter 5. Chapter 6. Chapter 7. Chapter 8. Chapter 9. Introduction
Factor VIII, factor VIII inhibitors, and phage display
Human antibodies with specificity for the C2 domain of factor VIII are derived from VH1 germline genes
Blood. 2000;95:558-563
Two classes of germline genes both derived from the VH1 family direct the formation of human antibodies that recognize distinct antigenic sites in the C2 domain of factor VIII
Manuscript in preparation
Multiple VH genes are used to assemble human antibodies toward the A3 domain of factor VIII
Submitted for publication
The missense mutation Arg593-»Cys is related to antibody
formation in a patient with mild hemophilia A
Blood. 1997;89:4371-4377
Longitudinal analysis of factor VIII inhibitors in a previously untreated mild haemophilia A patient with an Arg593->Cys substitution
Thromb Haemost. 1999;81:723-726
Molecular analysis of human anti-factor VIII antibodies by V gene phage display identifies a new epitope in the acidic region following the A2 domain
Blood. 2000;96:540-545
The primary structure and epitope map of the variable domains of factor VIII antibodies obtained from hemophilia A patients with inhibitors by V gene phage display
Submitted for publication
General discussion Summary/Samenvatting Curriculum vitae Nawoord 9 25 39 51 67 83 95 111 131 147 153 154
