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Intestinal Hedgehog signaling in tumors and inflammation

Büller, N.V.J.A.

Publication date

2015

Document Version

Final published version

Link to publication

Citation for published version (APA):

Büller, N. V. J. A. (2015). Intestinal Hedgehog signaling in tumors and inflammation.

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Stellingen

behorend bij het proefschrift

Intestinal Hedgehog Signaling in tumors and inflammation

1. Hedgehog signaling is essentieel voor het behoud van homeostase in het darmepitheel.

Dit proefschrift

2. Hedgehog responsieve cellen in de darm zijn gp38 positieve stromale cellen.

Dit proefschrift

3. Hedgehog signaling reguleert de expressie van de intestinale interferonrespons.

Dit proefschrift

4. Verlies van Hedgehog signaling onderdrukt het ontstaan van adenomen in de darm door fenotypische veranderingen van stromale cellen.

Dit proefschrift

5. Stromale cellen zijn belangrijk voor het ontstaan van adenomen in de darm.

Dit proefschrift

6. In ontstekingsgemedieerde tumoren resulteert het verlies van Hedgehog in een toename van tumoren.

Dit proefschrift

7. Teach thy tongue to say I do not know and thou shalt progress.

Maimonides

8. Argumenten moet men wegen, niet tellen.

Cicero

9. Whenever a theory appears to you as the only possible one, take this as a sign that you have neither understood the theory nor the problem which it was intended to solve.

Karl Popper

10. There is no such thing as mistakes, only happy accidents.

Bob Ross

11. Just do it

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