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Optimizing Patient Function After Musculoskeletal Trauma: An Introduction

Theodore Miclau, MDa, Esther M.M. Van Lieshout, MSc PhDb

a Orthopaedic Trauma Institute, Department of Orthopaedic Surgery, University of California, San Francisco, Zuckerberg San Francisco General Hospital, San Francisco, CA, USA

b Trauma Research Unit Department of Surgery, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands

Corresponding author:

Theodore Miclau, MD

Orthopaedic Trauma Institute

Department of Orthopaedic Surgery, University of California, San Francisco, Zuckerberg San Francisco General Hospital, San Francisco, CA, USA

Email: theodore.miclau@ucsf.edu

Phone: (628) 206-8812

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Abstract:

Trauma is a leading cause of morbidity and mortality worldwide. Post-traumatic conditions frequently result in long-term disabilities and represent significant socioeconomic challenges. Determining and addressing factors that influence function are essential for improving patient outcomes. This supplement seeks to highlight topical issues related to optimizing patient outcomes in order to better understand and improve post-injury care.

Introduction:

Trauma is the leading cause of death globally under the age of 40, exceeded only by

cardiovascular disease and cancer in all age groups (1,2). For every death due to injury, however, three individuals survive with permanent disabilities (3,4). The Global Burden of Disease Study 2013 Collaborators estimated that there were 22 million years lived with disability (YLD) due to fractures worldwide, accounting for over one-fifth of the global YLD burden in 2013, rising disability rates per person, and crucially significant health expenditures (5). Other reports estimate that surgical diseases account for approximately 11% of global disability-adjusted life years (DALYs) (6). Economic losses extend far beyond health care costs, as many individuals are unable to return to work due to physical and mental disabilities (7,8). Increases in injury-related disability are further being driven by an aging population and exacerbated by increased populations’ co-morbid conditions and physical inactivity (9,10).

Identifying and addressing elements that influence patient outcomes are critical to maximize patient recovery. While many factors are non-modifiable patient- and injury-related conditions, others can be significantly influenced by pre-operative, intraoperative, and post-operative

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management. To this end, treatment guidelines, pathways, and systems have been developed to standardize care and facilitate post-injury recovery (11-13). Further, methods to more reliably establish physical and psychological outcomes, which are critical for assessing and improving interventions, continue to advance with research and technology.

This supplement provides a review of topical issues related to optimizing patient function following musculoskeletal trauma. The work represents a summary discussion of those areas weighed during a recent international symposium hosted by the Osteosynthesis and Trauma Care Foundation in Toronto, Canada in November, 2019. The information presented in this

supplement will contribute towards greater efforts to understand and improve post-injury care worldwide.

Acknowledgement

The guest editors and all authors of this supplement thank the Osteosynthesis and Trauma Care Foundation (OTCF) for sponsorship of the symposium “Optimizing Patient Care Following Musculoskeletal Trauma” in Toronto, Canada, 2019 and of this supplement in Injury.

References

1. American College of Surgeons Committee on Trauma. Trauma Evaluation and Management Program for Medical Students. American College of Surgeons 1999.

2. Canada Research Chairs. Mohit Bhandari [Internet]. Canada Research Chairs. Available from: http://www.chairs-chaires.gc.ca/chairholders-titulaires/profile-eng.aspx?profileID=1598.

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3. The Subcommittee on Injury Prevention and Control. Injury Prevention. Presented at: American College of Surgeons Committee on Trauma 2003. Available at:

http://www.facs.org/trauma/injuryprevent.pdf.

4. National Trauma Registry Report 2013: Hospitalizations for Major Injury in Canada, 2010-2011 Data. Canadian Institute for Health Information 2013; Jan. Available at:

https://secure.cihi.ca/estore/productSeries.htm?locale=en&pc=PCC46.

5. Global Burden of Disease Study 2013 Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 2015;386(9995):743–800.

6. Jamison DT, Breman JG, Measham AR, et al. Disease control priorities in developing countries [Internet]. World Bank Publications; 2006 [cited 2015 Jun 22]

7. Sutherland, A, Alexander, DA, Hutchison, JD. Recovery after Musculoskeletal Trauma in Men and Women. J Trauma. 2005;59(1):213-216.

8. Clay FJ, Newstead SV, McClure RJ. A systematic review of early prognostic factors for return to work following acute orthopaedic trauma. Injury 2010;41(8):787-803.

9. Blagojevic M, Jinks C, Jeffery A, Jordan KP. Risk factors for onset of osteoarthritis of the knee in older adults: a systematic review and meta-analysis. Osteoarthritis Cartilage 2010;18:24– 33.

10. Greenstein AS, Gorczyca JT. Orthopedic Surgery and the Geriatric Patient. Clin Geriatr Med 2019;35(1):65-92.

11. Mock C, Lormand JD, Goosen J, Joshipura M, Peden M. Guidelines for essential trauma care. Geneva, World Health Organization, 2004.

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12. Mock C, Cherian MN. The global burden of musculoskeletal injuries: challenges and solutions. Clin Orthop Relat Res 2008;466:2306-2316.

13. Dijkink S, Nederpelt CJ, Krijnen P, Velmahos GC, Schipper IB. Trauma systems around the world: A systematic overview. J Trauma Acute Care Surg 2017;83(5):917-925.

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